AUTOIMMUNITY IN WISKOTT-ALDRICH SYNDROME: AN UNSOLVED ENIGMA

Autoimmunity in Wiskott-Aldrich Syndrome: an unsolved enigma

Wiskott-Aldrich Syndrome (WAS) is a severe X-linked Primary Immunodeficiency (PID) that affects 1 to 10 out of 1 million Collars male individuals.WAS is caused by mutations in the WAS Protein (WASP) expressing gene that leads to the absent or reduced expression of the protein.WASP is a cytoplasmic protein that regulates the formation of actin filam

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Heterogeneity in cardio-metabolic risk factors and atherosclerotic cardiovascular disease among Asian groups in the United States

Objective: The Asian American population in the U.S.comprises various, ethnically diverse subgroups.Traditionally, this population has been studied as a single, aggregated group, potentially masking differences in risk among subgroups.Analyses using disaggregated data can help better characterize the health needs of different Asian subpopulations a

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