Autoimmunity in Wiskott-Aldrich Syndrome: an unsolved enigma
Wiskott-Aldrich Syndrome (WAS) is a severe X-linked Primary Immunodeficiency (PID) that affects 1 to 10 out of 1 million Collars male individuals.WAS is caused by mutations in the WAS Protein (WASP) expressing gene that leads to the absent or reduced expression of the protein.WASP is a cytoplasmic protein that regulates the formation of actin filam